* 

姓名:聂刘旺

职称:教授

电话:0553-382288513705531693

邮箱:lwnie@ahnu.edu.cn

主要学习工作经历 

 


   

1984年皇冠新款入口获理学学士学位;

1998年南京师范大学获理学博士学位;

19846月——至今,皇冠新款入口工作。

主要社会兼职 

 

 


  中国遗传学会理事

  中国动物学会两栖爬行动物学分会副理事长

  安徽省遗传学会副理事长

  主要研究内容安徽省动物学会副理事长

 

 

 


  龟鳖类动物生物多样性及分子系统进化研究

  两栖爬行动物细胞遗传学及性别决定分子机制和性别人工控制研究

  医学分子生物学

  生物化感作用的分子机制

主要研究课题 

 

 


  国家自然科学基金项目,黄喉拟水龟性染色体的分化及温度诱导性别反转的分子机制。(No.32270553,2023-2026年,主持

  安徽省农业农村厅横向合作项目:安徽六安大别山区黄缘闭壳龟种质资源调查。2022-2024年,主持

  国家自然科学基金项目,乌龟和黄喉拟水龟种间杂交及杂种基因组的兼容性。(No.31970499),20202023年,主持

  国家自然科学基金项目,平胸龟线粒体DNA的重复控制区进化及转录组学研究(No.31372198),2014—2017年,主持

  国家星火计划重点项目子课题,草龟高效安全繁育与养殖技术集成与示范((2013GA710001))。20132014年,主持。

  国家自然科学基金项目,淡水龟科具闭壳结构龟类属间系统发生关系、分歧时间和我国分布物种多样性的研究(No.30970351),2010—2012年,主持

  教育部博士点专项科研基金,基于线粒体全序列和微卫星标记探讨我国四种龟类物种的有效性(20080370001),2009.1—2011.12年,主持

  国家自然科学基金,基于微卫星标记和线粒体全序列探讨中华鳖遗传多样性及两近缘物种的有效性(30770296),20082010年,主持

  国家自然科学基金,中华鳖分子系统地理学和两近缘物种有效性的研究(30640048),20072008年,主持

  国家自然科学基金,我国龟鳖目动物分子系统学的研究(30370211),20032004年,主持

  安徽省人力资源厅人才项目,闭壳龟类遗传保护研究,2017-2019年,主持







主要研究成果





 

 

 

 


代表性论文(*号为通讯作者):

1Liu Jianjun, Liu Siqi, Zheng Kai, Tang Min, Gu Liping, Young James, Wang Ziming, Qiu Yeyan, Dong Jinxiu, Gu Shengli, Xiong Lei, Zhou Ruanbao* & Nie Liuwang*. Chromosome-level genome assembly of the Chinese three-keeled pond turtle (Mauremys reevesii) provides insights into freshwater adaptation. Molecular Ecology Resource. 2021. DOI: 10.1111/1755-0998.13563Top期刊,一区)

2Gao Jiguang, Jiang Yu, Zheng Jiutao, Nie Liuwang *.Pubertal exposure to acrylamide disrupts spermatogenesis by interfering with meiotic progression in male mice. Toxicology Letters. 2022,358: 80–87(二区)

3Gao Ji-Guang, Yang Jian-Ke, Zhu Lei, Xu Cheng and Nie Liu-Wang *. Acrylamide impairs the developmental
potential of germinal vesicle oocytes by inducing mitochondrial dysfunction and autophagy/apoptosis in mice. Human and Experimental Toxicology. 2021, 40(12)
370–380  (四区)

4Dong Jinxiu, Liu Siqi, Wang Ziming, Zheng Kai, Yang Mengli, Liu Jianjun and Nie Liuwang *. The interaction between Tu-Izumo1 and Tu-JUNO is involved in turtles hybridization. Reproduction. 2021. 162: 33-42. DOI10.1530/REP-21-0124(二区)

5Gu Shengli, Liu Jianjun, Xiong Lei, Dong Jinxiu, Sun Entao, Hu Haoran, Yang Mengli, Nie Liuwang *. Morphological mechanism allowing a parasitic leech, Ozobranchus jantseanus (Rhynchobdellida: Ozobranchidae), tosurvive in ultra-low temperatures. Biology Open, 2021, DOI10.1242/bio.058524(三区)

6Xiong Lei , Yang Mengli, Zheng Kai, Wang Ziming, Gu Shengli, Tong Jiucui, Liu Jianjun , Nadar Ali Shah and Nie Liuwang. Comparison of Adult Testis and Ovary MicroRNA Expression Profiles in Reeves’ Pond Turtles (Mauremys reevesii) With TemperatureDependent Sex Determination. Frontiers in Genetics. 2020, 11:133. doi: 10.3389/fgene.2020.00133   (二区)

7Gong Yanan, Peng Lifang, Huang Song *, Lin Yanfeng, Huang Yi, Xu Yuhao, Yang Diancheng & Nie Liuwang *. A new species of the Genus Pelodiscus Fitzinger, 1835 (Testudines: Trionychidae) from Huangshan, Anhui, China. ZOOTAXA. 2021, 5060 (1): 137–145. doi /10.11646/zootaxa.5060.1.7(四区)

8Dong Jinxiu; Xiong Lei; Ding Hengwu; Jiang Hui; Zan Jiawei; Nie Liuwang *. Characterization of DNA Methylation and Transcript Abundance of Sex-related Genes during Temperature-dependent Sex Determination in Mauremys reevesii. Biology of Reproduction, 2020, 102(1):27-37 Doi:10.1093/biolre/ioz147(二区)

9Dong Jinxiu, Jiang Hui, Xiong Lei, Zan Jiawei, Liu Jianjun, Yang Mengli, Zheng Kai,Wang Ziming, Nie Liuwang*. Detecting coevolution of positively selected in turtles sperm-egg fusion proteins. Mechanisms of Development. 2019, 156:1-7. DOI: 10.1016/j.mod.2019.02.001(三区)

10Tong Jiucui, ZhouZ himing, Qi Weiwei, Jiang Siyan, Yang Bin, Zhong Zhengling, Jia Yuanwei, LiX uyi , Xiong Lei, Nie Liuwang,* Antidepressant effect of helicid in chronic unpredictable mild stress model in rats. International Immunopharmacology. 2019. 67:13-21.DOI: 10.1016/j.intimp.2018.11.052(二区)

11Xiong Lei, Dong Jinxiu, Jiang Hui, Zan Jiawei, Tong Jiucui, Liu Jianjun, Nie Liuwang*. Transcriptome sequencing and comparative analysis of ovary and testis identify potential key sex-related genes in Mauremys reevesii with temperature-dependent sex determination. PeerJ. 2019. DOI: 10.7717/peerj.6557.   (三区)

12Liu Jianjun, Jiang Hui, Zan Jiawei, Bao Yuantian, Dong Jinxiu, Xiong Lei &, Nie Liuwang *. Single-molecule long read transcriptome profiling of Platysternon megacephalum mitochondrialgenome with gene rearrangement and control region duplication . RNA BIOLOGY. 2018, 15( 9) :  1244-1249 . DOI: 10.1080/15476286.2018.1521212(二区)

13Yan Liang, Ma Jinzhu, Zhu Yiping, Zan Jiawei, Wang Zhen, Ling Liefeng, Li Qiang, Lv Jun, Qi Shimei, Cao Yingya, Liu Ying, Cao Long, Zhang Yao, Qi Zhilin, and Nie Liuwang *. miR-24-3p promotes cell migration and proliferation in lung cancer by targeting SOX7. Journal of Cellular Biochemistry. 2018, 119( 5): 3989-3998DOI 10.1002/jcb.26553(二区)

14Li Haifeng., Liu Jianjun., Xiong Lei., Zhang Huanhuan., Zhou Huaxin, Yin Huaxin., Li Jun., Shi Qiong., Wang Yuqin., Liu Juanjuan., Nie Liuwang*. Phylogenetic relationships and divergence dates of softshell turtles (Testudines: Trionychidae) inferred from complete mitochondrial genomes. Journal of Evolutionary Biology. 2017, Doi:10.1111/jeb.13070(三区)

15Bu Xingjiang*; Jiang Yanmei; Nie Liuwang*; Xia Xingquan. High frequency of multiple paternity in the Chinese soft-shelled turtle. Aquaculture Research, 2017, 48(9): 5155-5158(三区)

16Yin Huazong, Nie Liuwang*, Zhao Feifei, Zhou Huaxing, Li Haifeng, Dong Xianmei, Zhang Huanhuan, Wang Yuqin, Shi Qiong and Li Jun. De novo assembly and characterization of the Chinese three-keeled pond turtle (Mauremys reevesii)  transcriptome: presence of longevity-related genes. PeerJ. 2016, 4:e2062; DOI 10.7717/peerj.2062SCI收录)(三区)

17Zhou Huaxing, Jiang Yuan, Nie Liuwang*, Yin Huazong, Li Haifeng, Dong Xianmei, Zhao Feifei, Zhang Huanhuan, Pu Youguang, Huang Zhenfeng, Song Jiaolian, Sun Entao. The Historical Speciation of Mauremys Sensu Lato: Ancestral Area Reconstruction and Interspecific Gene Flow Level Assessment Provide New Insights. PLoS One, 2015, 10(12): e0144711. doi:10.1371/journal.pone.0144711SCI收录)

18Zheng Chenfei, Nie Liuwang *, Wang Jue, Zhou Huaxing, Hou Huazhen, Wang Hao, Liu Juanjuan. Recombination and Evolution of Duplicate Control Regions in the Mitochondrial Genome of the Asian BigHeaded Turtle, Platysternon megacephalum. PLoS One,2013, 8(12): e82854. doi:10.1371/journal.pone.0082854SCI收录)

19Sun En-Tao, Li Chao-Pin, Nie Liu-Wang*, Jiang Yu-Xin. The complete mitochondrial genome of the brown leg mite, Aleuroglyphus ovatus (Acari: Sarcoptiformes): evaluation of largest non-coding region and unique tRNAs. Exp Appl Acarol . 2014,  64:141–157. DOI 10.1007/s10493-014-9816-9ESISCI收录)

20Wang Ling, Zhou Xuming, Nie Liuwang *, Xia Xingquan, Liu Luo, Jiang Yuan, Huang Zhengfeng, Jing Wanxin. The complete mitochondrial genome sequences of Chelodina rugosa and Chelus fimbriata (Pleurodira: Chelidae): implications of a common absence of initiation sites (OL) in pleurodiran turtles. Mol Biol. Rep. 2012,  2097(11) (ISSN: 0301-4851) DOI 10.1007/s11033-011-0957-1SCI收录)

21Jiang Y., Nie L.W. *, Huang Z.F., Jing W.X., Wang L., Liu L. and Dai X.T.. Comparison of complete mitochondrial DNA control regions among five Asian freshwater turtle species and their phylogenetic relationships. 2011Genet. Mol. Res. 103):1545-155SCI收录)

22Zhang Ji-Feng, Nie Liuwang*, Wang Yang, Hu Li-Li, The complete mitochondrial genome of the large-headed frog, Limnonectes bannaensis (Amphibia: Anura), and a novel gene organization in the vertebrate mtDNAGene2009,442:119–127 SCI收录)

23Peng Qiao-Ling, Nie Liu-Wang*, Pu You-Guang, Complete mitochondrial genome of Chinese big-headed turtle, Platysternon megacephalum, and a novel gene organization in vertebrate mtDNA, 2006Gene, 380:14-20 SCI收录)

24Li Xiao-san, Nie Liu-wang*, Ling Wang, Lei Xiong, Ke Zhou. The mitochondrial genome complete sequence and organization of the Pig-nosed Turtle Carettochelys insculpta (Testudines,Carettochelyidae) and its phylogeny position in Testudines. Amphibia-Reptilia. 2010, 31: 541-551 ESISCI收录)

25Rui Jinlong, Wang Yuting, Nie Liuwang*The complete mitochondrial DNA genome of Eremias brenchleyi (Reptilia: Lacertidae) and its phylogeny position within squamata reptiles. Amphibia-Reptilia2009 301: 25-35 ESISCI收录)

26ZHANG T.T., HE M., WU A.P. and NIE L.W*. Allelopathic effects of submerged macrophyte Chara vulgaris on toxic Microcystis aeruginosa. Allelopathy Journal, 200923 (2): 391-402SCI收录)

专著:

  刘祥林 聂刘旺主编, 《基因工程》科学出版社,北京,20059

  安利国主编,杨桂文、聂刘旺副主编,《细胞工程》, 科学出版社,北京,2005

  王曼莹主编,聂刘旺等参编,《分子生物学》,科学出版社,北京,20067

  张锡然等主编,聂刘旺等参编,《分子细胞生物学进展》 南京皇冠新款入口出版社 1996

  单祥年主编,聂刘旺等参编 《临床基因诊断》 南京皇冠新款入口出版社 1999

专利:

  发明专利:乌龟血清对人肺癌细胞抑制作用的应用,授权专利号

ZL 201810344424.8

  发明专利:基于高通量测序筛选的乌龟微卫星DNA标记,授权专利号

  ZL 201710211233.X

  发明专利:中华鳖微卫星DNA标记,授权专利号ZL 201010528420.9

  发明专利:乌龟微卫星DNA标记,授权专利号ZL 201110026152.5

主要获奖情况:(省部级以上)

12016年,“两栖爬行动物的遗传学研究”获得安徽省科学技术奖(自然科学类)三等奖(主持人)。

22012年,“分子生物学基础课双语教学的模式与实践”获安徽省教育厅教学成果奖二等奖(本人排名第二)

32009年,获安徽省教育厅教学名师奖。

42007年,被安徽省教育厅评为全省优秀教师。